There have been recent, significant advances about the role of mrna turnover in controlling gene expression in immune cells. The first documented use of ndv for human cancer therapy was reported in 1964 by wheelock and dingle, where a patient with acute myelogenous leukemia was serially inoculated with multiple viruses in an attempt to induce remission. Their combined citations are counted only for the first article. The loss of pten function because of inactivating mutations that occur in tumors, such as those of prostate cancer, endometrial cancer, and glioblastoma, amplifies pi3kakt signaling and can subsequently lead to further aremrna stabilization of the cancer genes. Clinical practice guidelines for the prevention and. Molecular therapy vol 20, issue 5, pages 8771076 may 2012. This study significantly expands the repertoire of cancer genes that are regulated by rna stability proteins and how these interactions impact the cancer patient survival. The aurich elements ares are among the predominant cisacting factors that exist primarily in the 3 untranslated region 3utr of messenger rnas mrnas and regulate mrna stability. We also wanted to identify individuals who are most likely to use these methods and to compare the.
Singlewalled and multiwalled carbon nanotubes based drug. The goal of this journal is to provide a platform for scientists and academicians all over the world to promote, share, and discuss various new issues and developments in different areas of cancer therapy. Human antigen r hur is an rnabinding protein that regulates the stability, translation, and nucleustocytoplasm shuttling of its target mrnas. The prospective tumor suppressor tristetraprolin ttp has been shown to negatively regulate tumorigenesis through destabilizing the messenger rnas of critical genes implicated in both tumor onset and tumor progression. Selective estrogen receptor modulators or serm have been used to suppress tumor growth in estrogen dependent breast cancers and tamoxifen. Significance of cancer stem cells in anti cancer therapies validity of ratings of perceived exertion in patients with type 2 diabetes neural response during a mechanically assisted spinal manipulation in an animal model. Rasmy a, amal a, fotih s, selwi w 2016 febrile neutropenia in cancer patient. Oncolytic newcastle disease virus for cancer therapy. Pdf international journal of cancer therapy and oncology. School of pharmacy, faculty of medicine, the chinese university of hong kong, school of pharmacy, faculty of medicine, the chinese university of hong kong, school of pharmacy, faculty of. Pdf access policy full text access is free in html pages. A pilot study endothelial progenitor cells in breast cancer intranuclear inclusions in conventional clear cell renal cell. Journal of cancer therapy jct is an openly accessible journal published monthly.
Most of the studies related to the use of unconventional methods of therapy by cancer patients have been carried out in the developed countries. Use of unconventional methods of therapy by cancer. Colon cancer is a preventable, detectable and treatable malignancy, but yet remains the second leading cause of cancer deaths in georgia. Under the leadership of professor nieburgs the journal has become an international publication with an impact factor and coverage in pubmedmedline and many other. Cancer treatment and research communications journal elsevier.
Elsevier has purchased cancer detection and prevention from the international society for preventive oncology ispo. I n the healthy body, cellular posttranscriptional control contributes to rapid cytokine gene expression in response to inflammatory or microbial stimuli while allowing a transient reaction to the inducer. Education in saudi arabia is free at all levels and provided by the government. Coffee may protect against breast cancer, study shows date. Ares were previously believed to be restricted to relatively few mrnas, including those of interferons ifns and cytokines, growth factors, and protooncogenes. Epidemiology, microbiology, pathophysiology and management submit manuscript. Molecular therapy vol 20, issue 5, pages 8771076 may. Recently, the interferon ifn antiviral pathways and prostate cancer genetics and have surprisingly converged on a singlestrand specific, regulated endoribonuclease. The mrnas of many oncogenes, as well as regulators of other key processes such as cell proliferation. Posttranscriptional control of cytokine gene expression in. A research team evaluated 15 randomized controlled trials. If this control becomes aberrant, then extended and overproduction of proinflammatory cytokines and other mediators will exacerbate certain disease conditions khabar 2010. The first issue to be published under elsevier ownership is volume 32 issue 3.
Selwi w 2016 febrile neutropenia in cancer patient. Editorial board scholarena journal of cancer science open. Journal of cancer therapy impact factor abbreviation. Posttranscriptional control of the chemokine receptor cxcr4. Use of unconventional methods of therapy by cancer patients. Each issue of cancer strives to be comprehensive, spanning the breadth of oncology disciplines and providing something for everyone involved in cancer research, risk reduction, treatment, and.
Articles in press latest issue article collections all issues submit your article. Jct is an international journal dedicated to the latest advancements in cancer therapy. This 3d medical animation describes the process of intensity modulated radiation therapy, or imrt, including the use of ct scans and the linac. Cancer therapy and oncology international journal ctoij. Rnase l is upregulated with impaired function in lung cell lines. A preliminary assessment rumana dowla, annekathryn goodman, sadia akter. Cragg, natural products as sources of new drugs over the 30 years from 1981 to 2010 journal of. Researchers find immunotherapy treatments better for advanced.
Boron neutron capture therapy bnct is based on the atomic response that happens when boron10 is irradiated with lowenergy thermal neutrons to yield highdirect energy exchange. Indian journal of cancer is the first and only periodical serving the needs of all the specialties of oncology in india. Regulation of ttp has therefore emerged as an important issue in tumorigenesis. During tumorigenesis the transformed cells lose their normal growth control mechanisms and become dependent on oncogenes products and pathways for survival. After much research and careful consideration, we have decided to expand the scope of the journal to encompass cancer epidemiology, in addition to cancer detection and prevention. The association of cxcr4 expression with clinicopathological significance and potential drug target in prostate cancer. To investigate the expression feature of rnase l in lung cancer cells lines, ncih157, glc82. Treatments tailored to block the expression or function of transforming genes have shown efficacy in eliminating neoplastic cells. Advanced hepatocellular carcinoma with distant metastases. Hnsccs secrete multiple cytokines including vegf, il. Singlewalled and multiwalled carbon nanotubes based drug delivery system.
Because collection of frozen tissue is not practical for routine surgical pathology practice, a clinical test. If detected early, colon cancer cure rate can be high as 95%. Safety concerns for hpv vaccination of young generation, paid by obamacare and v. Researchers find immunotherapy treatments better for. Novel drug delivery approach in cancer therapy open access. International journal of cancer therapy and oncology evaluation of surface dose outside the treatment area for five breast cancer irradiation modalities using thermoluminescent dosimeters. Ksa khabar, ma elbarbary, f khouqeer, e devol, s al. Journal of cancer metastasis and treatment is an open access journal, focusing on basic and clinical studies related to cancer cell, cell biology, oncology. Because of the great potential application of ndds in cancer therapy we are enabled the development of novel therapeutic and diagnostic strategies 46. Read featured content on cancer research, treatment regimens and clinical studies. The concept of bnct was first introduced by locher. Latest cancer articles, treatment info, research news and more for oncologists and medical professionals. Journal of biological chemistry 278 14, 1208512093, 2003. Posttranscriptional control of the chemokine receptor.
Epidemiology, microbiology, pathophysiology and management. Journal of cancer therapy rg journal impact rankings. In the field of cntbased drug delivery system, both singlewalled carbon nanotubes swcnts and multiwalled nanotubes mwcnts can be used for targeting anticancer drugs in tissues and organs, where the high therapeutic effect is necessary. Journal of cancer science and therapy open access journals. The former addresses the posttranscriptional control of cytokines that promote procancer activities, particularly in angiogenesis griseri and pages 2014. Cancer is one of the major public health cause in the world. Biden moonshot initiative lob vaccines immunol, 2016 doi. Mci aims to encourage comprehensive, multiprofessional cancer research. Jul 15, 2016 this study reveals a hitherto unknown generic mechanism for largescale metabolic reprogramming in cancer cells, based on linear gene proximities between cancer causing and metabolic genes, with the identification of 119 genes likely to be involved in rewiring cancer cell metabolism. Crystallins were firstly found as structural proteins of the eye lens.
Other notable but less common malignancies seen in our patients were ovarian cancer 7. Program in biomolecular research, king faisal specialist hospital and research center, riyadh, saudi arabia. Learn more about coping with cancer by journaling and reading inspiring books and stories told by cancer patients and survivors. Jct is an international journal dedicated to the latest advancement of cancer therapy. Coffee may protect against breast cancer, study shows. Adisintegrin and metalloproteinase adam 17 enzymatically. Novel drug delivery approach in cancer therapy open. Editorial board scholarena journal of cancer science. These findings underscore the necessity to translate these potential biomarkers into clinical practice. National cancer institute, and others have sought to bring to the attention of the oncology community the clinical and economic impact of mucosal injury secondary to highdose cancer therapy. Genetics studies from several laboratories in the u. Program in biomolecular research, king faisal specialist hospital and research center, p3354, mbc. Oncology international journal is dedicated to publish the contributions on all aspects of experimental and clinical cancer research. The stability of mrna is one of the key factors governing the regulation of eukaryotic gene expression and function.
Nov 04, 2016 a research team evaluated 15 randomized controlled trials published between 2011 and 2015, assessing the benefits and harms of targeted or immune checkpoint inhibitors in 6,662 patients with. Pdf type i interferons and dendritic cells in cancer. This cited by count includes citations to the following articles in scholar. Every year, cancer is responsible for millions of deaths worldwide and, even.
Ksa khabar, ma elbarbary, f khouqeer, e devol, s algain, z alhalees. This study reveals a hitherto unknown generic mechanism for largescale metabolic reprogramming in cancer cells, based on linear gene proximities between cancercausing and metabolic genes, with the identification of 119 genes likely to be involved in rewiring cancer cell metabolism. Transcription inhibition as a therapeutic target for cancer. The majority of published gene signatures of crc have been generated on fresh frozen colorectal tissues. The hallmarks of cancer refer to a concept in which the authors of the original paper narrow cancer as a disease to six features, and later, these features were upgraded with two enabling and two hallmarks of cancer. The goal of this journal is to provide a platform for doctors and academicians all over. Foods that could lower your risk of cancer september 27, 2019 september 25, 2019 2 comments.
Journal of cancer treatment and research science publishing. From january 2020 cancer treatment and research communications is an open access journal. Gene mutatio ns, copy number aberrations and dna methylations provided promising biomarkers for the detection, diagnosis, prognosis, therapy response and targets of ovarian cancer. The compliance for colon cancer screening in georgia is poor, particularly among the indian community. Implications for rnase l in prostate cancer biology.
Journal of cancer therapeutics and research open access. Its international repute is recognized by its indexing with most bibliographic databases. Prevalence of various cancer related risk factors among the forcibly displaced myanmar national community, the rohingya, in bangladesh. Indian journal of cancer issn 0019509x, the show window of the progress of oncological sciences in india, was established in 1963. Posttranscriptional control of cytokine gene expression. Intravenous inoculation with ndv hickman strain resulted in rapid reduction in leukemic blast count and. What you eat can drastically affect many aspects of your health, including your risk of developing chronic diseases like heart disease, diabetes and cancer. Researchers find immunotherapy treatments better for advanced skin cancer date. Carbon nanotubes cnts are advanced nanocarrier for delivery of drugs especially anti cancer drugs.
Saudi oncology society, saudi cancer society and saudi cancer foundation are nonprofit bodies established to improve cancer care and prevention. To study the metabolic adaptation for survival occurring in the cancer cells. Limited published data suggest pancreatic cancer patients undergoing carbon ion therapy and proton therapy achieve a comparable median survival time 25. To investigate the expression feature of rnase l in lung cancer cells lines, ncih157, glc82, calu3, lteps, ncih520, ncih209. The goal of this journal is to provide a platform for doctors and academicians all over the world to promote, share, and discuss various new issues and developments in cancer related problems. Genetic loss or mutations in tumor suppressor genes promote tumorigenesis. The prognosis of colorectal cancer crc stage ii and iii patients remains a challenge due to the difficulties of finding robust biomarkers suitable for testing clinical samples. Scholarena journal of cancer science sajcs from scholarena journals has a strong editorial board to maintain the quality of open access research articles.
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